Work

Acute Acquired Fanconi Syndrome in Multiple Myeloma After Hematopoietic Stem Cell Transplantation

Year: 2020

Type: article

Abstract: Although a rare complication, proximal tubular dysfunction of the kidneys can occur in patients with monoclonal gammopathies, including multiple myeloma (MM).1–3 Light chain proximal tubulopathy (LCPT) can occur with or without Fanconi syndrome (FS), which is the result of nonselective kidney wasting of electrolytes, uric acid, glucose, and amino acids. Clinical presentation includes hypokalemia, hypophosphatemia, proximal renal tubular acidosis (RTA), hypouricemia, normoglycemic glycosuria, and aminoaciduria.

Source: Kidney International Reports

DOI: 10.1016/j.ekir.2020.12.007