Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet
Year: 2019
Type: article
Source: Cell
Authors: Chia-Wei Cheng, Moshe Biton, Adam L. Haber, Nuray Gunduz, George Eng, Liam T. Gaynor, Surya Tripathi, Gizem Calibasi-Kocal, Steffen Rickelt, Vincent L. Butty, Marta Moreno-Serrano, Ameena M. Iqbal, Khristian E. Bauer-Rowe, Shinya Imada, Mehmet Sefa Ulutas, Constantine Mylonas, Mark T. Whary, Stuart S. Levine, Yasemin Basbinar, Richard O. Hynes, Mari Mino-Kenudson, Vikram Deshpande, Laurie A. Boyer, James G. Fox, Christopher Terranova, Kunal Rai, Helen Piwnica-Worms, Maria M. Mihaylova, Aviv Regev, Ömer H. Yilmaz
Institutions: Koch Institute for Integrative Cancer Research At MIT, Broad Institute, Harvard University, Massachusetts General Hospital, Klarman Cell Observatory, Massachusetts Institute of Technology, Bilkent University, National Nanotechnology Research Center, Dana-Farber Cancer Institute, Dokuz Eylül University, Hiroshima University, Siirt Üniversitesi, Howard Hughes Medical Institute, The University of Texas MD Anderson Cancer Center, The Ohio State University
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: bronze
Funders: Howard Hughes Medical Institute, Pew Charitable Trusts, American Federation for Aging Research, Alexander and Margaret Stewart Trust, V Foundation for Cancer Research, Helen Hay Whitney Foundation, Sidney Kimmel Foundation, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, National Institutes of Health, Klarman Cell Observatory, Broad Institute, Ludwig Center at Harvard, National Institute on Aging, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: Elucidating the role of fasting in intestinal stemness and tissue regeneration, G1944922328, G1991958910, Understanding the Mechanisms of Age-Dependent Decline of Intestinal Stem Cell Function, Understanding the Mechanisms of Age-Dependent Decline of Intestinal Stem Cell Function, An integrated translational approach to overcome drug resistance, Dietary control of stem cells in physiology and cancer, Regulation of the Intestinal Stem Cell Niche in Aging, G589803372, Elucidating the role of fasting in intestinal stemness and tissue regeneration, G6251337527, Impact of Cellular and Extracellular Host Components on Tumor Progression, Fasting Protects Small Intestinal Stem Cells from Lethal DNA Damage: Mechanistic Insight and Preclinical Translation, Understanding and Improving Platinum Anticancer Drugs, Molecular Immunology and Tumor Biology, Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital, G910680712
OpenAlex ID: W2969784858