Heart Sound Analysis in Individuals Supported With Left Ventricular Assist Devices: A First Look
Year: 2020
Type: conference-paper
Study design: Observational Study
Abstract: The left ventricular assist device (LVAD) has emerged as a bridge or alternative to heart transplant in individuals with advanced heart failure.However, the LVAD recipient population currently faces high rehospitalization rates.Remote analysis of precordial sounds in LVAD recipients may improve aftercare through early detection of complications.Prior work on analyses of precordial sounds in LVAD recipients focused on identifying pump thrombosis.Here, we focus on analyzing intrinsic precordial sounds to provide insight into intrinsic cardiac function.We analyzed a dataset of patient-acquired recordings of precordial sounds in LVAD recipients.We developed a signal processing pipeline to separate LVAD-generated sounds from other precordial sounds, making heart sound analysis in LVAD recipients feasible.Unsupervised clustering of features extracted from LVAD-mitigated sounds revealed subgroups of subjects possessing heart sounds with distinct frequency characteristics.The results provide preliminary evidence for the potential utility of exploring heart sound analysis in LVAD recipients for remote monitoring. MethodsSignal processing and analysis were performed using MATLAB© (The MathWorks, Inc.). Data DescriptionTwenty-four patients were recruited at Duke University Hospital for a study approved by the Duke Health Institutional Review Board.Sixteen subjects had a
Source: Computing in cardiology
Institutions: Duke University, Duke Medical Center
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W3119297609