Work

Flow-Through Micro-Electroporation Chip for Genetic Engineering of Individual Cells

Year: 2002

Type: conference-paper

Abstract: We describe a chip that is capable of performing gene transfer in individual biological cells through single cell microelectroporation. Microfluidic channels are used to handle individual cells in a flow through fashion that yields high electroporation efficiency.Controlled introduction of macromolecules and genetic engineering of an individual cell are demonstrated.

Source: Solid-State Sensors, Actuators, and Microsystems Workshop (Hilton Head Workshop)

DOI: 10.31438/trf.hh2002.50

Authors: Y. Huang, B. Rubinsky

Institution: University of California, Berkeley

Language: English

Topic: Microbial Inactivation Methods

Subfield: Biotechnology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funder: National Institutes of Health

OpenAlex ID: W3119379109

FWCI:

Cites: 9

Cited by: 2

Related to: 10