Work

Longer antibiotic durations for treating peritoneal dialysis-associated peritonitis: helpful or harmful?

Year: 2020

Type: editorial

Abstract: Relapsing, recurrent or repeat peritonitis is a devastating complication for peritoneal dialysis (PD) patients and is usually associated with poor outcomes including prolonged hospitalization, catheter removal, hemodialysis transfer and even death. Despite its critical importance and frequent occurrence, there is limited available evidence to facilitate evidence-informed treatment of PD peritonitis. This editorial comments on the findings and limitations of a randomized controlled study published in this journal, which reported that extending antibiotic treatment duration for an additional week beyond that recommended by the International Society for PD did not reduce the risk of relapsing, recurrent or repeat peritonitis, and may have increased the risk of repeat peritonitis. These results are explored in the context of the existing literature and recommendations for practice and research are provided.

Source: Clinical Kidney Journal

DOI: 10.1093/ckj/sfaa277

Authors: Htay Htay, Yeoungjee Cho, David W Johnson

Institutions: Singapore General Hospital, Translational Research Institute, The University of Queensland, Princess Alexandra Hospital

Language: English

Topic: Dialysis and Renal Disease Management

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,335