Work

YI 1.2 Ideal Cardiovascular Health Score Declines from Adolescence to Emerging Adulthood

Year: 2020

Type: article

Abstract: Purpose To define and compare cardiovascular (CV) health scores (CHS) from adolescence (17 yrs) to emerging adulthood (24 yrs) using longitudinal data from a large British birth cohort. Methods 3142 participants from the Avon Longitudinal Study of Parents and Children (ALSPAC) study attended clinical investigations at 17.8 ± 0.4 yrs and 24.0 ± 0.8 yrs (38% male). CV health was assessed using smoking status, body mass index (BMI), plasma glucose, cholesterol, sitting brachial blood pressure, left ventricle (LV) hypertrophy, arterial stiffness (carotid-to-femoral pulse wave velocity) and atherosclerosis (carotid intima-media thickness) metrics. Prevalence was stratified into poor (0_points), intermediate (1_point) and ideal (2_points) health categories and a composite, individual-level CHS for all 8 metrics was calculated (total range, 0–16 points). Prevalence of ideal health was assessed using ANOVA and linear mixed modelling assessed age##sex modifications. Results Overall CHS was high at 17 yrs but from 17–24 yrs the proportion of ideal scores decreased for all metrics, in both sexes (Table). The average overall CHS decreased from 14.97 ± 1.1 to 13.99 ± 1.4 in males (p < 0.0001) and 14.82 ± 1.2 to 14.28 ± 1.4 in females (p < 0.0001, age##sex p = 0.0001). Significant sex differences were observed in the proportion of individuals with ideal health at both ages, with males having a higher CHS than females at 17 yrs but a lower CHS at 24 yrs. Conclusions Despite being relatively early in the life-course, CV health declines from 17 yrs to 24 yrs in both sexes, and more substantially in males. Emerging adulthood is a distinct period of lifestyle change and an important time to control CV risk factors to improve future CV health. Table Male 0 1 Age 17 yrs 24 yrs Age0 Age1 Age2 Age3 Age4 Score 0 1 2 0 1 2 p 0 Score0 Score1 Score2 Score3 Score4 Smoking 22.6 19.3 58.1 27.8 35.6 36.6 <0.0001 27.8 Smoking0 Smoking1 Smoking2 Smoking3 Smoking4 BMI 4.9 13.3 82.1 10.4 30.0 59.6 <0.0001 6.7 BMI0 BMI1 BMI2 BMI3 BMI4 Glucose 0.4 9.1 90.5 0.6 34.7 64.7 <0.0001 0.3 Glucose0 Glucose1 Glucose2 Glucose3 Glucose4 Cholesterol 0.0 1.5 98.5 2.1 11.7 86.2 <0.0001 0.1 Cholesterol0 Cholesterol1 Cholesterol2 Cholesterol3 Cholesterol4 Blood pressure 0.2 0.5 99.3 0.6 5.4 94.0 <0.0002 0.3 Blood pressure0 Blood pressure1 Blood pressure2 Blood pressure3 Blood pressure4 LV hypertrophy 0.6 0.6 98.9 1.4 3.7 94.8 <0.0001 0.5 LV hypertrophy0 LV hypertrophy1 LV hypertrophy2 LV hypertrophy3 LV hypertrophy4 Arterial stiffness 0.5 0.9 98.6 4.8 6.7 88.5 <0.0001 0.0 Arterial stiffness0 Arterial stiffness1 Arterial stiffness2 Arterial stiffness3 Arterial stiffness4

Source: Artery Research

DOI: 10.2991/artres.k.201209.002