Work

The N-terminal domain of the adaptor protein p140Cap interacts with Tiam1 and controls Tiam1/Rac1 axis.

Year: 2020

Type: article

Abstract: expression. Overall, our findings sustain a protective role of p140Cap in Her2 positive breast cancer, where p140Cap can associate with Tiam1 and negatively regulate the Tiam1/Rac1 axis.

Source: PubMed

Authors: Jennifer Chapelle, Annalisa Baudino, Federico Torelli, Aurora Savino, Alessandro Morellato, Costanza Angelini, Vincenzo Salemme, Giorgia Centonze, Dora Natalini, Marta Gai, Valeria Poli, Thilo Kähne, Emilia Turco, Paola Defilippi

Institutions: University of Turin, Otto-von-Guericke-Universität Magdeburg

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3120188742

FWCI: 0.428

Cites: 47

Cited by: 7

Related to: 10