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A robust unsupervised machine-learning method to quantify the morphological heterogeneity of cells and nuclei

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Year: 2021
Type: article
Source: Nature Protocols
DOI: 10.1038/s41596-020-00432-x
Authors: Jude M. Phillip, Kyu-Sang Han, Wei-Chiang Chen, Denis Wirtz, Pei-Hsun Wu
Institutions: Johns Hopkins University, Johns Hopkins Medicine, Sidney Kimmel Comprehensive Cancer Center
Language: English

Topic: Cell Image Analysis Techniques
Subfield: Biophysics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: green

Funders: U.S. Department of Health and Human Services, National Institutes of Health, National Institute on Aging, National Cancer Institute
Awards: G1373639953, G1912770925, Single-cell phenotyping for therapeutic stratification in pancreatic cancer, G2909399862, G601512365, The Johns Hopkins Physical Sciences Oncology Center, G7079668014, Validation of Nuclear Morphology as a Biomarker of Aging and Aging-Related Phenotypes, Older Americans Independence Center, Center for Cancer Physics
OpenAlex ID: W3120345372
FWCI: 7.566
Cites: 76
Cited by: 118
Related to: 10
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