Work

Stem cell origins of JMML

Year: 2021

Type: article

Abstract: In this issue of JEM, Louka et al. (https://doi.org/10.1084/jem.20180853) report that leukemia stem cells lie within the phenotypic hematopoietic stem cell and progenitor cell compartments in juvenile myelomonocytic leukemia (JMML). Furthermore, they identify several candidate biomarker/therapeutic targets, such as CD96 and SLC2A1, that are of translational significance in JMML.

Source: The Journal of Experimental Medicine

DOI: 10.1084/jem.20202152

Authors: Sriram Sundaravel, Ulrich Steidl

Institutions: Albert Einstein College of Medicine, Montefiore Medical Center

Language: English

Topic: Acute Myeloid Leukemia Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Cancer Research UK, Blood Cancer UK, Medical Research Council, National Cancer Institute