Effect of high salt intake on plasma lipid profile in pregnant wistar rats.
Year: 2020
Type: article
Abstract: day, the animals were fasted overnight and sacrificed under anaesthesia. Blood samples were collected via cardiac puncture for determination of lipid parameters triglyceride (TG), total cholesterol (TC), high density lipoprotein-cholesterol (HDL-c), low density lipoprotein-cholesterol (LDL-c), and very low density lipoprotein-cholesterol (VLDL-c) using enzymatic colorimetric method. Atherogenic indices, triglyceride/HDL-C (TG/HDL-C) and total cholesterol/HDL-C (TC/HDL-C) ratios were calculated. SPSS 21.0 package was used for data analysis and level of significance was analyzed using student t-test. Significance was set at P<0.05. Result showed significant (P<0.05) increases in plasma level of TG, TC, LDL-C VLDL-C, TG/HDL-C and TC/HDL-C ratios in high salt fed pregnant rats compared to control. No significant (P>0.05) change was observed in HDL-C level in high salt fed pregnant rats when compared with control. High salt intake during pregnancy has detrimental effect on maternal lipid profile which can threaten both maternal and the fetal life.
Source: PubMed Central
Authors: Folasade O Ajao, Marcus O Iyedupe
Institution: Ladoke Akintola University of Technology
Language: English
Topic: Sodium Intake and Health
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3124163146