Year: 2021
Type: review
Study design: Systematic Review
Abstract: Cerebral palsy (CP) neurologic care and research efforts typically focus on children. However, most people with CP are adults. Adults with CP are at increased risk of new neurologic conditions, such as stroke and myelopathy, that require ongoing neurologic surveillance to distinguish them from baseline motor impairments. Neurologic factors could also contribute to the motor function decline, chronic pain, and chronic fatigue that are commonly experienced by adults with CP. Based on a systematic literature review, we suggest (1) guidelines for neurologic surveillance and neurologist referral and (2) clinical research questions regarding the evolving neurologic risks for adults with CP. ANN NEUROL 2021;89:860-871.
Source: Annals of Neurology
DOI: 10.1002/ana.26040
Institutions: Washington University in St. Louis, University of Hartford, Shriners Hospitals for Children, University of Michigan, Michigan Medicine, University of Pennsylvania, University of Minnesota, Gillette Children's Specialty Healthcare, Barrow Neurological Institute, University of Arizona, Phoenix Children's Hospital, University of Arizona College of Medicine- Phoenix, University of Chicago, Nationwide Children's Hospital, The Ohio State University, University of Pittsburgh, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Awards: Mechanisms Underlying the Pathogenic Role of an α-Adducin/α2-Na/K ATPase Complex in Amyotrophic Lateral Sclerosis, G3428435397, Early Life Seizures Disrupt Critical Period Plasticity, Genomic Insights into the Neurobiology of Cerebral Palsy, National Research Service Award-Medical Scientist, Child Neurologist Career Development Program, G940110195
OpenAlex ID: W3126188978