Work

The Complex Link between the Female Genital Microbiota, Genital Infections, and Inflammation

Year: 2021

Type: review

Abstract: spp. are well known to have adverse effects; however, the definitive cause of this microbial dysbiosis is yet to be fully elucidated. The aim of this review is to discuss the multiple ways in which the microbiota influences the overall genital inflammatory milieu and to explore the causes and consequences of this inflammatory response. While there is abundant evidence linking a diverse genital microbiota to elevated inflammation, understanding the risk factors and mechanisms through which it affects genital health is essential. A robust appreciation of these factors is important for identifying effective prevention and treatment strategies.

Source: Infection and Immunity

DOI: 10.1128/iai.00487-20

Authors: Smritee Dabee, Jo-Ann S. Passmore, Renee Heffron, Heather B. Jaspan