Work

Bile Acids: Connecting Link Between Autophagy and Gut Microbiome

Year: 2021

Type: article

Abstract: Bile acids are amphiphilic molecules earlier known only for their role in digestion but more recently found to be critically involved in intraorgan and interorgan signaling.1 Their role in establishing communication between organs, such as liver, gut, heart, and brain, has been well documented.2,3 Increases in bile acid levels are generally injurious to health. Particularly, chronic bile acid elevation leads to liver injury and hepatocellular carcinoma.4 However, at normal levels, bile acids play a major role in maintaining gut health and regulating liver regeneration.

Source: Cellular and Molecular Gastroenterology and Hepatology

DOI: 10.1016/j.jcmgh.2021.01.010

Author: Udayan Apte

Institution: University of Kansas Medical Center

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500