Work

Treatment Updates in Antineutrophil Cytoplasmic Autoantibodies (ANCA) Vasculitis

Year: 2021

Type: review

Abstract: ANCA vasculitis is a small-vessel vasculitis (SVV) resulting in inflammation of small- and medium-sized blood vessels. Since the initial description of SVV, there have been tremendous advances in our understanding of its pathogenesis. Over the last decade, we have made significant progress in understanding the pathogenesis and improving the treatment and prognosis of patients with ANCA vasculitis. Patient and renal survival has improved, and treatment is moving toward individualizing care, minimizing severe adverse events, and preventing relapse. This review focuses on treatment updates in ANCA vasculitis, duration of therapy, and management of relapses. We also describe the existing treatment protocols used at our institution.

Source: Kidney360

DOI: 10.34067/kid.0007142020

Authors: Koyal Jain, Pankaj Jawa, Vimal K. Derebail, Ronald J. Falk

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Vasculitis and related conditions

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: National Institute of Diabetes and Digestive and Kidney Diseases