Work

A practical guide for the management of acute abdominal pain with fever in patients with autosomal dominant polycystic kidney disease

Year: 2021

Type: article

Abstract: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of numerous renal cysts leading to kidney enlargement and chronic kidney disease (CKD) [1]. Extrarenal manifestations, including polycystic liver disease (PLD) and connective tissue defects, are frequently observed in ADPKD. Acute cyst complications such as haemorrhage (CyH) and infection (CyI) represent rare but severe conditions of ADPKD [2, 3]. The distinction between cystic versus non-cystic abdominal complications is problematic [3]. We propose a practical guide for the diagnostic and therapeutic management of ‘acute abdominal pain with fever’ in patients with ADPKD. An episode of febrile acute abdominal pain is a clinical challenge. The primary task of the physician consists of rapidly distinguishing patients who can be safely observed from patients who require hospitalization and specialist referral (Figure 1). The quickSOFA score has been developed to screen for patients at risk...

Source: Nephrology Dialysis Transplantation

DOI: 10.1093/ndt/gfab040

Authors: François Jouret, Marie C Hogan, Fouad T Chebib

Institutions: University of Liège, Centre Hospitalier Universitaire de Liège, Mayo Clinic

Language: English

Topic: Genetic and Kidney Cyst Diseases

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3127542841