Work

Very low field 19F MRI of perfluoro-octylbromide: Minimizing chemical shift effects and signal loss due to scalar coupling

Year: 2021

Type: article

Abstract: 19F images have been obtained from perflurooctylbromide (PFOB) at very low magnetic field (50 mT). The small spectral dispersion (in Hz) means that all fluorine nuclei contribute to the signal without chemical shift artifacts or the need for specialized imaging sequences. Turbo spin echo trains with short interpulse intervals and full 180° refocussing pulses suppress scalar coupling, leading to long apparent T2 values and highly efficient data collection. Overall, the detection efficiency of PFOB is very similar that of water in tissue.

Source: Journal of Magnetic Resonance

DOI: 10.1016/j.jmr.2021.106946

Authors: Javad Parsa, Thomas O'Reilly, Andrew Webb

Institution: Leiden University Medical Center

Language: English

Topic: Advanced MRI Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: hybrid

Estimated APC paid: $3,300

Funders: Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Horizon 2020 Framework Programme, H2020 European Research Council