Work

Outcomes of acute hepatitis B virus (HBV) in HIV infection with and without HBV-active antiretroviral therapy

Year: 2021

Type: article

Abstract: Men with acute hepatitis B virus (HBV) infection in the Multicenter AIDS Cohort Study from 1985 to 2013 had serological testing to determine proportions with HBV recovery or chronic hepatitis B (CHB). A similar proportion of men without human immunodeficiency virus (HIV) and men with HIV receiving HBV-active antiretroviral therapy (ART) developed CHB [8.2%, 95% confidence interval (CI) 3.8-15.0% vs. 7.7%, 95% CI 2.00-36.0%]. In contrast, 17.5% (95% CI 8.7-29.9%) of men living with HIV, not on HBV-active ART developed CHB. HBV-active ART protects against developing CHB.

Source: AIDS

DOI: 10.1097/qad.0000000000002844

Authors: Oluwaseun Falade-Nwulia, Eric C. Seaberg, Anna E. Snider, Charles R. Rinaldo, Steven M. Wolinsky, Mallory D. Witt, Chloe L. Thio

Institutions: Johns Hopkins University, University of Pittsburgh, Northwestern University, University of California, Los Angeles, The Lundquist Institute, Harbor–UCLA Medical Center

Language: English

Topic: Hepatitis B Virus Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Allergy and Infectious Diseases, National Center for Advancing Translational Sciences

Awards: G2755707676, G343705321, G4816384646, Center/Coordination, Analysis and Management/MACS, G785655061, MACS/WIHS -CCS, The Johns Hopkins Center for AIDS Research (JHU CFAR), Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS) - Baltimore/Wash DC Center, UCLA Clinical and Translational Science Institute

OpenAlex ID: W3131866355

FWCI: 0.611

Cites: 10

Cited by: 10

Related to: 10