Work

Nipping Adipocyte Inflammation in the Bud

Year: 2021

Type: article

Abstract: Adipose tissue inflammation continues to represent a significant area of research in immunometabolism. We have identified a transcription factor, EBF1, which crucially regulates the expression of numerous inflammatory loci in adipocytes. However, EBF1 appears to do so without physically binding to these inflammatory genes. Our research is currently focused on understanding this discrepancy, and we believe that future findings could pave the road for drug development aimed to block adipose inflammation at its source.

Source: Immunometabolism

DOI: 10.20900/immunometab20210012

Author: Michael J. Griffin

Institution: Sam Houston State University

Language: English

Topic: Adipokines, Inflammation, and Metabolic Diseases

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: National Institute of Diabetes and Digestive and Kidney Diseases