Year: 2020
Type: article
Study design: Observational Study
Abstract: Objective To assess the frequency of malignancy in female patients presenting with mastalgia without any other symptoms. Study design Observational study. Place & Duration of study General Surgery, Civil Hospital Karachi, from June 2018 to January 2019. Methodology The demographic profile of study participants, type and severity as duration of pain with presence of breast lump, family and menstrual history, use of hormone replacement therapy (HRT) and comorbid conditions were evaluated. Findings on physical and radiologic examination were then reviewed to assess its relationship with the patient's characteristics. A tru-cut biopsy was performed in those having higher BIRADS lesions to confirm the diagnosis of malignancy. Results A total of 158 patients were included. The mean age of patients was 39.8±11.9 year. Majority of the patients (n=111 - 70.3%) were pre-menopausal. The most common symptom was mild pain reported in 73 (46.2%) patients. Eighty-two (51.9%) patients had breast imaging reporting and data system (BIRADS) I grade of radiological lesions. Statically significant relationship was identified between BIRADS classification and type of pain (p=0.018) and with severity of pain (p<0.001). Patients with higher BIRADS scores had non-cyclic and severe pain in post-menopausal period with palpable mass in breast. Conclusion Higher BIRADS grading was found significantly more in patients with non-cyclical pain and with higher frequency of malignancy on histopathology. Key words Mastalgia, Post-menopausal, Breast cancer, Malignancy.
Source: Journal of surgery Pakistan
Author: Saeed Ahmed
Institutions: Civil Hospital Karachi, Dow University of Health Sciences
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W3132817632
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