Work

HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis

Year: 2021

Type: article

Source: Cell stem cell

DOI: 10.1016/j.stem.2021.02.008

Authors: Kaosheng Lv, Chujie Gong, Charles Antony, Xu Han, Jian-Gang Ren, Ryan Donaghy, Ying Cheng, Simone Pellegrino, Alan J. Warren, Vikram R. Paralkar, Wei Tong

Institutions: Children's Hospital of Philadelphia, University of Pennsylvania, Wellcome/MRC Cambridge Stem Cell Institute, University of Cambridge

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: St. Baldrick's Foundation, Wellcome Trust, Kay Kendall Leukaemia Fund, European Cooperation in Science and Technology, Blood Cancer UK, National Institutes of Health, Medical Research Council, NIHR Cambridge Biomedical Research Centre, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: Joint Wellcome and MRC Centre, ‘Wellcome Trust – Medical Research Council Cambridge Stem Cell Institute’, Regulation of protein ubiquitination in hematopoietic cytokine signaling, Lnk Regulatory Functions in Hematopoietic Stem Cells, G4483131783, Molecular mechanisms of eukaryotic ribosome assembly, Cellular Medicine at the Cambridge Institute for Medical Research., G5999869015, Regulation of Ribosome Biogenesis in Hematopoietic Stem Cells, Cellular Medicine at the Cambridge Institute for Medical Research., Cambridge Stem Cell Institute, G8315929747, Regulation of rRNA transcription in mammalian tissues

OpenAlex ID: W3133612898

FWCI: 8.932

Cites: 62

Cited by: 84

Related to: 10