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Mesenchymal stem cells overexpressing BMP-9 by CRISPR-Cas9 present high in vitro osteogenic potential and enhance in vivo bone formation

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Year: 2021
Type: article
Source: Gene Therapy
DOI: 10.1038/s41434-021-00248-8
Authors: Gileade P. Freitas, Helena B. Lopes, Alann T. P. Souza, Maria Paula O. Gomes, Georgia K. Quiles, Jonathan Gordon, Coralee Tye, Janet L. Stein, Gary S. Stein, Jane B. Lian, Marcio M. Beloti, Adalberto L. Rosa
Institutions: Universidade de São Paulo, University of Vermont
Language: English

Topic: Mesenchymal stem cell research
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institute of General Medical Sciences, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Dental and Craniofacial Research
Awards: Chromatin Organization Regulates Osteogenesis, Control of Osteoblast Proliferation and Differentiation, Northern New England Clinical and Translational Research Network
OpenAlex ID: W3134333094
FWCI: 3.161
Cites: 59
Cited by: 54
Related to: 10
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