Work

Structure of Rad5 provides insights into its role in tolerance to replication stress

Year: 2021

Type: editorial

Abstract: The Rad5 family of proteins are critical genome maintenance factors, with helicase-like transcription factor (HLTF) and SNF2 histone linker PHD RING helicase (SHRPH) in humans implicated in several types of cancer. How their multiple activities coordinate has been unclear. Our recent study on Rad5 shed light on this question.

Source: Molecular & Cellular Oncology

DOI: 10.1080/23723556.2021.1889348

Authors: Miaomiao Shen, Nalini Dhingra, Quan Wang, Xiaoxin Gong, Xin Xu, Hengyao Niu, Xiaolan Zhao, Song Xiang

Institutions: Tianjin Medical University, Memorial Sloan Kettering Cancer Center, Indiana University Bloomington, Indiana University

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, National Cancer Institute

Awards: G1199820600, G8204572421, Cancer Center Support Grant

OpenAlex ID: W3134647265

Cites: 10

Cited by: 1

Related to: 10