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Recapitulating the Binding Affinity of Nrf2 for KEAP1 in a Cyclic Heptapeptide, Guided by NMR, X-ray Crystallography, and Machine Learning

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Year: 2021
Type: article
Source: Journal of the American Chemical Society
DOI: 10.1021/jacs.0c09799
Authors: Paula C. Ortet, Samantha N. Muellers, Lauren A. Viarengo-Baker, Kristina Streu, Blair R. Szymczyna, Aaron B. Beeler, Karen N. Allen, Adrian Whitty
Institution: Boston University
Language: English

Topic: Chemical Synthesis and Analysis
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: closed

Funders: American Association of University Women, Genentech, National Institute of General Medical Sciences, Division of Graduate Education
Awards: G3372011863, A Synchrotron Radiation Structural Biology Resource, Center for Biomolecular Structure (CBMS)
OpenAlex ID: W3135372416
FWCI: 2.117
Cites: 62
Cited by: 46
Related to: 10
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