Work

Evaluation of HIV-1 Latency Reversal and Antibody-Dependent Viral Clearance by Quantification of Singly Spliced HIV-1 vpu / env mRNA

Year: 2021

Type: article

Abstract: and humanized mouse models, we showed that the vpu/env assay could be used to measure antibody efficacy in clearing HIV-1 infection. These results suggest that the vpu/env assay can accurately evaluate HIV-1 reactivation and bNab-based therapeutic interventions.

Source: Journal of Virology

DOI: 10.1128/jvi.02124-20

Authors: Hongbo Gao, Ayşe N. Ozantürk, Qiankun Wang, Gray H. Harlan, Aaron J. Schmitz, Rachel M. Presti, Kai Deng, Liang Shan

Institutions: Sun Yat-sen University, Washington University in St. Louis

Language: English

Topic: HIV Research and Treatment

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Yale University, Regeneron Pharmaceuticals, National Institute of Allergy and Infectious Diseases

Awards: G1221903865, G6511232711

OpenAlex ID: W3136205605

FWCI: 1.236

Cites: 53

Cited by: 14

Related to: 10