Work

Assessment of retinal microvascular health by optical coherence tomography angiography among persons with HIV

Year: 2021

Type: article

Study design: Observational Study

Abstract: Microvasculopathy may link HIV-related chronic inflammation and premature multimorbidity. In this proof-of-concept study, we used optical coherence tomography angiography (OCTA) to evaluate the retina as a convenient assessment of microvascular health among persons with HIV (PWH) undergoing surveillance ophthalmic care at Emory from 2018 to 2021. Among patients with longstanding HIV, OCTA identified microvascular abnormalities even among eyes without clinical retinal disease. Retinovascular evaluation by OCTA is a feasible, noninvasive technique for assessing microvasculopathy among PWH.

Source: AIDS

DOI: 10.1097/qad.0000000000002890

Authors: Lauren F. Collins, Jessica G. Shantha, Peter L. Nesper, Anandi N. Sheth, Amani A. Fawzi, Steven Yeh, Ighovwhera Ofotokun

Institutions: Grady Memorial Hospital, Emory University, Grady Health System, Northwestern University, Emory Global Health Institute

Language: English

Topic: Retinal Diseases and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute on Aging, National Eye Institute, National Institute of Allergy and Infectious Diseases, National Center for Advancing Translational Sciences

Awards: Ophthalmic Disease and Laboratory Surveillance in a Viral Hemorrhagic Fever Zone, Pathogenesis of Uveitis in Ebola Virus Disease Survivors, Emory Specialized Center of Research Excellence (SCORE) on Sex Differences, Institutional Career Development Core, Center for AIDS Research at Emory University, Georgia Clinical & Translational Science Alliance (Georgia CTSA)

OpenAlex ID: W3137017391

FWCI: 1.568

Cites: 25

Cited by: 11

Related to: 10