Work

Author response: The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function

Year: 2021

Type: peer-review

Abstract: SWELL1 is required for basal, stretch, and flow-mediated endothelial AKT-eNOS signaling in vitro and protects against angiotensin-induced hypertension and diabetes-associated vascular dysfunction in vivo.

Source: eLife

DOI: 10.7554/elife.61313.sa2

Authors: Ahmad F Alghanem, Javier Abello, Joshua M Maurer, Ashutosh Kumar, Chau My Ta, Susheel K Gunasekar, Urooj Fatima, Chen Kang, Litao Xie, Oluwaseun Adeola, Megan Riker, Macaulay Elliot-Hudson, Rachel A Minerath, Chad E Grueter, Robert F Mullins, Amber N Stratman, Rajan Sah

Institutions: King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Washington University in St. Louis, University of Iowa

Language: English

Topic: Nitric Oxide and Endothelin Effects

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W3137983167

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