Abstract P6: Impact of Ethnicity on the Outcomes of Mechanical Thrombectomy- Insights From Star
Year: 2021
Type: conference-abstract
Abstract: Introduction: Previous studies have reported that Hispanic stroke patients have limited access to mechanical thrombectomy (MT) compared to other ethnic groups. This has resulted in worse stroke outcomes in this group. However, limited data is available about the outcomes of MT in Hispanic patients. Methods: We used data from the Stroke Thrombectomy and Aneurysm Registry (STAR) that combined the prospectively maintained databases of 28 thrombectomy-capable stroke centers in the US, Europe, and Asia. Consecutive patients who underwent MT were included in these analyses and patients were divided into 2 groups (Hispanics vs. non-Hispanics). Baseline features, time from symptom onset, thrombolysis receipt, final thrombolysis in cerebral infarction (TICI) score, symptomatic hemorrhage, and 90-day functional outcomes (measured by modified Rankin scale-mRS) were compared between Hispanic and non-Hispanics patients. A generalized linear model with logit link was used to assess the relationship between ethnicity and favorable outcomes at 90-day (mRS 0-2) controlling for confounders. Results: We included 2015 patients in these analyses. Of those, 285 (14.1%) were Hispanic. As shown in table 1, Hispanic patients were older (72 vs. 70, p=0.007), more likely to have diabetes (41.1% vs. 26.5%, p<0.001), and more likely to have hypertension (81.8% vs. 73.7%, p=0.004). Importantly, Hispanics had a shorter procedure duration with a similar rate of successful recanalization (TICI≥2B). On multivariable analysis, Hispanic ethnicity was associated with a lower probability of favorable 90-day outcome (aOR 0.659, 95% CI 0.494-0.879, P=0.005) after controlling for age, stroke risk factors and location of occlusion. Conclusion: Hispanic patients receiving MT have higher rate of stroke risk factors including diabetes and hypertension. Moreover, Hispanic ethnicity was independently associated with lower probability of favorable 90-day outcome.
Source: Stroke
Authors: Eyad Almallouhi, Sami Al Kasab, Ali Alawieh, Stephanie Chen, JOSHUA BURKS, Stacey Wolfe, Pascal M Jabbour, Michael Levitt, Adam S Arthur, Reade A De Leacy, Jonathan A Grossberg, Christopher S Ogilvy, Min S Park, Daniel Raper, Adam Polifka, R. Webster Crowley, Travis Dumont, Joshua Osbun, Roberto Crossa, Ilko Maier, Joon-Tae Kim, Walter Casagrande, Ansaar Rai, Shakeel Chowdhry, Maxim Mokin, Charles Matouk, Isabel Fragata, Richard Williamson, Albert J Yoo, Justin Mascitelli, Peter Kan, Marios Psychogios, Kyle Fargen, Robert Starke, Alejandro M Spiotta
Institutions: Medical University of South Carolina, University of Miami, Wake Forest University, Thomas Jefferson University, University of Washington, Semmes Murphey Foundation, Mount Sinai Hospital, Emory University, Beth Israel Deaconess Medical Center, University of Virginia, Baylor College of Medicine, University of Florida, Rush University, University of Arizona, Washington University in St. Louis, Universitätsmedizin Göttingen, Chonnam National University, Chonnam National University Hospital, Hospital Fernández, West Virginia University, Endeavor Health, University of South Florida, Yale University, Allegheny Health Network, The University of Texas at San Antonio Health Science Center, The University of Texas Medical Branch at Galveston, University Hospital of Basel
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3138142973