Reply to “Phase II prospective randomized trial of weight loss prior to radical prostatectomy”
Year: 2018
Type: letter
Abstract: We commend Henning et al. [ 1 ] and their randomized controlled trial of a weight loss intervention (WLI) among prostate cancer patients in the presurgical setting. Abbreviated study periods and complicated logistics make these trials challenging. We speak from experience, since we completed a trial of similar design [ 2 , 3 , 4 ]. While Henning et al. discussed our trial [ 1 , 2 , 3 ], our findings were not presented, possibly due to publication overlap [ 4 ]. Both trials were undertaken with the same scientific premise: weight loss would slow tumor proliferation and reduce biomarkers of insulin signaling, inflammation, and androgenic control. Thus, we submit this letter to compare and contrast these two pioneering efforts.
Institutions: University of Alabama at Birmingham, UAB Medicine
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $5,190
OpenAlex ID: W3141637691