Work

Molecular Mechanism of Cannabinoids in Cancer Progression

Year: 2021

Type: article

Abstract: Cannabinoids are a family of heterogeneous compounds that mostly interact with receptors eliciting several physiological effects both in the central and peripheral nervous systems and in peripheral organs. They exert anticancer action by modulating signaling pathways involved in cancer progression; furthermore, the effects induced by their use depend on both the type of tumor and their action on the components of the endocannabinoid system. This review will explore the mechanism of action of the cannabinoids in signaling pathways involved in cancer proliferation, neovascularisation, migration, invasion, metastasis, and tumor angiogenesis.

Source: International Journal of Molecular Sciences

DOI: 10.3390/ijms22073680

Authors: Cristina Pagano, Giovanna Navarra, Laura Coppola, Maurizio Bifulco, Chiara Laezza

Institutions: University of Naples Federico II, Institute for Experimental Endocrinology and Oncology

Language: English

Topic: Cannabis and Cannabinoid Research

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,160