Work

Replicated risk CACNA1C variants for major psychiatric disorders may serve as potential therapeutic targets for the shared depressive endophenotype.

Year: 2020

Type: article

Abstract: might confer the genetic vulnerability to the shared depressive symptoms across MPDs and CACNA1C might be the therapeutic target for depressive endophenotype as well.

Source: PubMed

Authors: Xiaoyun Guo, Yingmei Fu, Yong Zhang, Tong Wang, Lu Lu, Xingqun Luo, Kesheng Wang, Juncao Huang, Ting Xie, Chengchou Zheng, Kebing Yang, Jinghui Tong, Lingjun Zuo, Longli Kang, Yunlong Tan, Kaida Jiang, Chiang-Shan R Li, Xingguang Luo

Institutions: Shanghai Jiao Tong University, Shanghai Mental Health Center, Yale University, Shanghai Key Laboratory of Psychotic Disorders, Tianjin Anding Hospital, University of Tennessee Health Science Center, Fujian University of Traditional Chinese Medicine, East Tennessee State University, Beijing HuiLongGuan Hospital, Xizang Minzu University

Language: English

Topic: Genetic Associations and Epidemiology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institutes of Health

Awards: A noradrenergic mechanism of apathy and motivation deficit in MCI and AD, Post-GWAS transcriptome-wide LncRNA expression profiling in alcohol dependence, Sequencing of glutamatergic pathway genes in alcohol and nicotine co-dependence, Deep sequencing of genes in ethanol-metabolism pathway in alcoholism

OpenAlex ID: W3142552932

FWCI: 0.146

Cites: 38

Cited by: 3

Related to: 10