Work

Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot–Marie–Tooth Type 2A Mouse Model

Year: 2021

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c02210

Authors: Sida Shen, Cristina Picci, Kseniya Ustinova, Veronick Benoy, Zsófia Kutil, Guiping Zhang, Maurício T. Tavares, Jiří Pavlíček, Chad A. Zimprich, Matthew B. Robers, Ludo Van Den Bosch, Cyril Bařinka, Brett Langley, Alan P. Kozikowski

Institutions: University of Illinois Chicago, University of Waikato, Czech Academy of Sciences, Institute of Biotechnology, VIB-KU Leuven Center for Brain & Disease Research, KU Leuven, Promega (United States)

Language: English

Topic: Histone Deacetylase Inhibitors Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Institute on Aging, National Institute of Neurological Disorders and Stroke, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: Study of the New HDAC6i SW-100 as a Treatment for Alzheimer’s Disease and Other Tauopathies, AN HDAC6 APPROACH TO RETT SYNDROME, Optimization of HDAC6 Inhibitors in the Treatment of CMT

OpenAlex ID: W3143002850

FWCI: 1.959

Cites: 53

Cited by: 35

Related to: 10