The effects of extracts of Atractylodes macrocephala koidz combined with transcutaneous electrical acupoint stimulation in treating the ovariectomized female rats
Year: 2016
Type: article
Abstract: Background: The present study was to explore the effects of the extracts of Atractylodes macrocephala Koidz (EAMK) combined with transcutaneous electrical acupoint stimulation (TEAS) on the ovariectomized female rats.Materials and Methods: Forty female Sprague-Dawley rats were randomly divided into four groups: sham-operation, model, livial and EAMK+TEAS groups (n=10 in each group). After the individual treatments for 8 weeks ended, the serum levels of estradiol (E2), follicle stimulating hormone (FSH), luteinizing hormone (LH), osteocalcin and interleukin-6 (IL-6) were measured with commercial enzyme-linked immunosorbent assay.Results: We found that in the sham-operation group, the serum E2 and osteocalcin levels were significantly higher, and the serum levels of FSH, LH and IL-6 were markedly lower than those of other groups (P<0.05). No significant differences existed between the livial and EAMK+TEAS groups on the serum E2 and osteocalcin levels (P>0.05), however, the serum FSH and IL-6 levels of EAMK+TEAS group were significantly lower than those of the livial group (P<0.05).Conclusion: EAMK combined with TEAS has promises in treating the ovariectomized female rats.Keywords: Extracts of Atractylodes macrocephala Koidz (EAMK), transcutaneous electrical acupoint stimulation (TEAS), osteocalcin, interleukin-6 (IL-6)
Authors: Qing Weng, Zhu-Feng Cao, Yan-Wen Yu, Xiang-Lin Lv, Fan Qu, Jue Zhou
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W3143332374