Work

Severe Hypoglycemia Associated With Oral Sotalol Use in Two Children

Year: 2021

Type: article

Abstract: Hypoglycemia is a rare but recognized side effect of anti-beta-adrenergic medications (beta-blockers) commonly used to manage arrhythmias in children. In 2014 a commercially available premixed solution of sotalol became available, and the use of oral sotalol in children has increased. Hypoglycemia associated with sotalol use has not been previously reported. Sotalol contains a racemic mixture of its D- and L-enantiomers and although it primarily acts to block Ikr (potassium channels), the L-enantiomer has nonselective anti-beta-adrenergic effects.

Source: HeartRhythm Case Reports

DOI: 10.1016/j.hrcr.2021.03.020

Authors: Christina Y. Miyake, Jeffrey J. Kim, Mustafa Tosur, Taylor S. Howard, Tam Dan N. Pham, Santiago O. Valdes

Institutions: Baylor College of Medicine, Texas Children's Hospital

Language: English

Topic: Cardiac electrophysiology and arrhythmias

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,050