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The synthesis of furoquinolinedione and isoxazoloquinolinedione derivatives as selective Tyrosyl-DNA phosphodiesterase 2 (TDP2) inhibitors

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Year: 2021
Type: article
Source: Bioorganic Chemistry
DOI: 10.1016/j.bioorg.2021.104881
Authors: Hao Yang, Xiao-Qing Zhu, Wenjie Wang, Yu Chen, Zhu Hu, Yu Zhang, De-Xuan Hu, Le-Mao Yu, Keli Agama, Yves Pommier, Lin-Kun An
Institutions: Sun Yat-sen University, National Institutes of Health, National Cancer Institute, Center for Cancer Research
Language: English

Topic: Synthesis and biological activity
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute
Award: DNA Repair, Cell Cycle Checkpoints and Apoptosis as Targets for Anticancer Drugs
OpenAlex ID: W3144958168
FWCI: 0.831
Cites: 46
Cited by: 11
Related to: 10
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