Work

Nipping disease in the bud: nSMase2 inhibitors as therapeutics in extracellular vesicle-mediated diseases

Year: 2021

Type: review

Source: Drug Discovery Today

DOI: 10.1016/j.drudis.2021.03.025

Authors: Carolyn Tallon, Kristen R. Hollinger, Arindom Pal, Benjamin J. Bell, Rana Rais, Takashi Tsukamoto, Kenneth W. Witwer, Norman J. Haughey, Barbara S. Slusher

Institutions: Johns Hopkins University, Johns Hopkins Medicine

Language: English

Topic: Extracellular vesicles in disease

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute on Aging, National Institute of Mental Health, National Institute on Drug Abuse, National Cancer Institute, National Institute of Allergy and Infectious Diseases

Awards: Regulation of Exosome Secretion as a novel therapeutic approach for Alzheimer's Disease, Translational Research in Neuro-AIDS and Mental Health, Dendrimer-conjugated nSMase2 inhibitor as a novel therapeutic approach for Alzheimer's Disease, Novel Separation Methods for exRNA Carriers: Extracellular Vesicles, Lipoprotein Particles, and Protein Aggregates, Next-generation extracellular vesicle biologics to target central nervous system and peripheral reservoirs of HIV, Extracellular Vesicle and Extracellular RNA Biomarkers of HIV-1 Central Nervous System Pathogenesis and Cigarette Use, JHU Center for the Advancement of HIV Neurotherapeutics (JHU CAHN), Novel Approaches to Capture, Sorting, and Characterization of CNS-Origin Extracellular Vesicles

OpenAlex ID: W3149234028

FWCI: 0.918

Cites: 118

Cited by: 67

Related to: 10