Modulating Specific Central and Peripheral Pathways to Effectively Treat Obesity
Year: 2014
Type: article
Abstract: Dysregulation of the homeostatic control of appetite and hepatic glucose production, and the imbalance of the interrelation between the gut microbiota and the innate immune system, are currently believed to be the main causes of obesity. Most of these mechanisms function by interacting with one another, rendering high levels of complexity in continual maintainance of a stable body weight. Understand the molecule that acts specifically or having a regulatory role in each of the pathway, is therefore crucial in effective management of obesity development. A number of function-specific mechanisms and pathways of the hypothalamus and the gut have been identified as potential therapeutic targets.
Author: Chooi Yeng Lee
Language: English
Subfield: Endocrine and Autonomic Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W2319678447