Work

TET2 mediated demethylation is involved in the protective effect of triptolide on podocytes.

Year: 2021

Type: article

Abstract: , we found that TP could protect against podocyte injury in the FSGS rat and increase TET2 expression. These results suggested TET2-mediated DNA demethylation may be partly involved in podocyte injury. We believe these findings can help uncover a novel molecular mechanism of TP in alleviating podocyte-associated glomerular diseases.

Source: PubMed

Authors: Feng Wan, Yue-Wen Tang, Xuan-Li Tang, Ya-Yu Li, Ru-Chun Yang

Institution: Zhejiang Chinese Medical University

Language: English

Topic: Renal Diseases and Glomerulopathies

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3154657181

FWCI: 2.347

Cites: 33

Cited by: 15

Related to: 10