Work

Development of a Core Outcome Set for Studies on the Prevention and Management of Pregnancy-associated Venous Thromboembolism

Year: 2020
Type: dissertation
Abstract: Background: The objective of this thesis was to identify a list of outcomes to consider in the development of a core outcome set (COS) to inform future studies on pregnancy-associated venous thromboembolism (VTE), with aim of standardizing outcome reporting. Methods: We conducted a systematic review (Study-1) of 70 studies and 18 interviews (Study-2) with health service users and healthcare professionals, to generate a list of outcomes and inform a two-part online Delphi survey (Study-3). Results: Studies-1 and 2 identified 35 and 57 outcomes, respectively, which were condensed to 45 unique outcomes. The Delphi survey included 81 participants in round-1 and 66 in round-2 including health service users, clinicians and academics, representing 21 countries. Conclusion: We have attained consensus on outcomes that should be considered in the COS for future studies on pregnancy-associated VTE.
Language: English
Open Access status: green
OpenAlex ID: W3155371621
Cites: 60
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Related to: 10