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Adjunctive therapy for multidrug-resistant bacterial infections: Type III secretion system and efflux inhibitors

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Year: 2021
Type: review
Source: Drug Discovery Today
DOI: 10.1016/j.drudis.2021.03.031
Authors: Donald T. Moir, Timothy J. Opperman, Zachary D. Aron, Terry L. Bowlin
Institution: Microbiotix (United States)
Language: English

Topic: Antibiotic Resistance in Bacteria
Subfield: Molecular Medicine
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Wellcome Trust, Bundesministerium für Bildung und Forschung, Asian Society for Pediatric Research, National Institutes of Health, Biomedical Advanced Research and Development Authority, National Institute of Allergy and Infectious Diseases
Awards: Validating targets in p. aeruginosa type III secretion using chemical probes, Optimization of novel pyranopyridine efflux pump inhibitors, Antibiotic Potentiators Targeting SOS Induction, G7140082099, Type III Secretion Inhibitors for Anti-Infective Therapy, T3SS needle protein inhibitors for the treatment of P. aeruginosa infection
OpenAlex ID: W3155876301
FWCI: 0.238
Cites: 75
Cited by: 16
Related to: 10
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