Work

Author response: Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics

Year: 2021

Type: peer-review

Abstract: High-level transposon insertional mutagenesis and a broader spectrum of resistance-conferring mutations for selected carbapenems facilitate the evolution of carbapenem resistance in Klebsiella pneumonia clinical isolates.

Source: eLife

DOI: 10.7554/elife.67310.sa2

Authors: Peijun Ma, Lorrie L He, Alejandro Pironti, Hannah H Laibinis, Christoph M Ernst, Abigail L Manson, Roby P Bhattacharyya, Ashlee M Earl, Jonathan Livny, Deborah T Hung

Institutions: Broad Institute, Harvard University, Massachusetts General Hospital, Center for Computational and Integrative Biology, Massachusetts General Hospital

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W3157827973

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