Work

Haven't got a glue: Protein surface variation for the design of molecular glue degraders

Year: 2021

Type: review

Source: Cell chemical biology

DOI: 10.1016/j.chembiol.2021.04.009

Authors: Zuzanna Kozicka, Nicolas Holger Thomä

Institutions: University of Basel, Friedrich Miescher Institute

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Novartis Foundation, European Commission, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Oncosuisse, European Research Council, Horizon 2020, H2020 European Research Council

Awards: G1821380202, European Research Training to Decipher The Ub Code : identification of potential biomarkers and drug targets, Targeting DNA Replication Stress through Novel Small-Molecule Degraders in Cancer, G6465635744, The molecular basis of CULLIN E3 ligase regulation by the COP9 signalosome

OpenAlex ID: W3158527646

FWCI: 2.489

Cites: 111

Cited by: 170

Related to: 10