Year: 2016
Type: article
Abstract: With its unique tautomerase activity, macrophage migration inhibitory factor (MIF) is a multi-functional pro-inflammatory cytokine implicated in the pathogenesis of numerous types of cancer. Through a variety of mechanisms MIF is tumourigenic, pro-inflammatory and pro-angiogenic. As a result of its central role in both cancer and inflammation many MIF inhibitors are currently in development, with recent studies yielding impressive results.
Source: Trinity Student Medical Journal
Author: Hartnett, Jack
Institution: Trinity College Dublin
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
Funder: Trinity College Dublin
OpenAlex ID: W3158549318