Year: 2007
Type: article
Abstract: Statins: A review of benefits and risks Siobhra O'Sullivan 4th Year Medicine • Statins have cholesterol and non-cholesterol (pleiotropic) effects • Statins are central in the prevention of cardiovascular events associated with increased blood lipids and atherosclerotic lesions • Recent and ongoing trials are investigating the benefits of early and intensive statin therapy versus current regimens, with promising results so far • Cerivastatin was withdrawn in 2001 due to increased risk of rhabdomyolysis.Currently marketed statins have a superior safety profile, with the incidence of serious toxicities being extremely rare • For at-risk patients, morbidity and mortality from cardiovascular events are greatly reduced with longterm statin use Clinical Points 52
Source: Trinity Student Medical Journal
Author: O’Sullivan, Siobhra
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W3158620416