Work

Novel STAT3 small-molecule inhibitors identified by structure-based virtual ligand screening incorporating SH2 domain flexibility

Year: 2021

Type: article

Source: Pharmacological Research

DOI: 10.1016/j.phrs.2021.105637

Authors: Ren Kong, Uddalak Bharadwaj, T. Kris Eckols, Mikhail Kolosov, Haoyi Wu, Francisco J. Santa Cruz-Pavlovich, Alison Shaw, Oluwatomilona I. Ifelayo, Hong Zhao, Moses M. Kasembeli, Stephen T.C. Wong, David J. Tweardy

Institutions: Houston Methodist, Jiangsu University of Technology, Weill Cornell Medicine, The University of Texas MD Anderson Cancer Center

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Computational Theory and Mathematics

Field: Computer Science

Domain: Physical Sciences

Open Access status: bronze

Funders: National Natural Science Foundation of China, National Institutes of Health, University of Texas MD Anderson Cancer Center, National Cancer Institute

Awards: Center for Systematic Modeling of Cancer Development, Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors

OpenAlex ID: W3159475770

FWCI: 0.923

Cites: 77

Cited by: 22

Related to: 10