The application value of oXiris-endotoxin adsorption in sepsis.
Year: 2021
Type: article
Abstract: OBJECTIVES: This study explored and analyzed the application value of oXiris- endotoxin adsorption technology in patients with sepsis. METHODS: 23 sepsis patients hospitalized from January 2018 to September 2019 in our ICU center and received oxiris-endotoxin adsorption were enrolled as the observation group, and another 30 sepsis patients hospitalized during the same period were selected as the control group who treated with routine continuous renal replacement therapy (CRRT). The heart rate, respiratory rate, norepinephrine (NE) dosage, lactic acid, procalcitonin (PCT), urine volume, and sofa scores that evaluate organ failure after systemic infection, as well as ICU stay, organ support duration, and incidence of cardiovascular events were compared between the two groups before and after treatment. RESULTS: ). CONCLUSION: compared with the traditional CRRT technology, the oXiris membrane based CRRT technology can effectively improve the hemodynamic indicators of patients with sepsis, reduce the level of inflammation, and improve the metabolic function of body, thereby improving the patients' organ function. It has good clinical application value in patients with sepsis.
Source: PubMed
Authors: Yanping Zhai, Jiayu Pan, Chunyun Zhang
Institution: Guangzhou Medical University
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3160662541