Work

Individuals who were mildly symptomatic following infection with SARS-CoV-2 B.1.1.28 have neutralizing antibodies to the P.1 variant

Year: 2021

Type: preprint

Abstract: Objectives To evaluate if antibodies induced by infection with a different SARS-CoV-2 virus strain neutralize the P.1 variant. Methods Convalescent sera from 60 individuals following a documented SARS-CoV-2 infection were assayed for neutralizing antibody titer against both strains. Results Fifty-six and 50 sera were positive for neutralizing antibodies against the ancestral and P.1 strains, respectively. Neutralization titers were higher against the ancestral strain, but in the majority of patients differences did not differ by more than a single dilution. Conclusions Neutralizing antibodies that were generated following infection with SARS-CoV-2 B.1.1.28 were effective in vitro , against the SARS-CoV-2 P.1. variant.

Source: medRxiv

DOI: 10.1101/2021.05.11.21256908