Work

Tissue Engineering: Stabilization of Damaged Articular Cartilage with Hydrogel‐Mediated Reinforcement and Sealing (Adv. Healthcare Mater. 10/2021)

Year: 2021

Type: article

Abstract: In article number 2100315 by Robert L. Mauck and co-workers, a hyaluronic acid (HA) system is used to modify the surface of damaged cartilage. This interdigitating microenvironment enhances the multi-scale mechanics of degenerated cartilage, restoring the response of chondrocytes within. This modified tissue surface can then be used to improve the adhesion and behavior of stem cells, providing a route to “seal” cartilage defects. Together, this combined reinforcement and sealing may present an innovative therapy for the treatment of damaged cartilage.

Source: Advanced Healthcare Materials

DOI: 10.1002/adhm.202170049

Authors: Jay M. Patel, Claudia Loebel, Kamiel S. Saleh, Brian C. Wise, Edward D. Bonnevie, Liane M. Miller, James L. Carey, Jason A. Burdick, Robert L. Mauck

Language: English

Topic: Osteoarthritis Treatment and Mechanisms

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W3161273097

FWCI: 0.313

Cites:

Cited by: 2

Related to: 10