Bilobalide alleviates neuroinflammation and promotes autophagy in Alzheimer's disease by upregulating lincRNA-p21.
Year: 2021
Type: article
Abstract: experiments revealed that bilobalide improved the learning and memory capabilities of APP/PS1 AD mice. Bilobalide improves the cognitive functions of APP/PS1 AD mice. Mechanistically, bilobalide suppresses inflammatory responses and promotes autophagy possibly by upregulating lincRNA-p21 levels.
Source: PubMed Central
Authors: Yi-Ren Qin, Chi-Qian Ma, Da-Peng Wang, Quan-Quan Zhang, Mei-Rong Liu, Hong-Ru Zhao, Jian-Hua Jiang, Qi Fang
Institution: First Affiliated Hospital of Soochow University
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W3161662293