Work

Discovery of novel N-1 substituted pyrazolopyrimidinones as potent, selective PDE2 inhibitors

Year: 2021

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2021.128082

Authors: Gregori J. Morriello, Michael P. Dwyer, Yili Chen, Anthony T. Ginetti, Shimin Xu, Jun Lu, Pravien Abeywickrema, Deping Wang, Alejandro Crespo, Tamara D. Cabalu, Jonathan E. Wilson, Shawn J. Stachel, Daniel V. Paone, Christopher Sinz

Institution: Merck & Co., Inc., Rahway, NJ, USA (United States)

Language: English

Topic: Phosphodiesterase function and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W3161802304

FWCI: 0.157

Cites: 15

Cited by: 4

Related to: 10