Work

Author response: T cell self-reactivity during thymic development dictates the timing of positive selection

Year: 2021

Type: peer-review

Abstract: Developing T cells whose TCRs have relatively low reactivity experience very brief TCR signaling events, experience delayed positive selection, and retaina preselection gene expression signature as they mature.

DOI: 10.7554/elife.65435.sa2

Authors: Lydia K Lutes, Zoë Steier, Laura L McIntyre, Shraddha Pandey, James Kaminski, Ashley R Hoover, Silvia Ariotti, Aaron Streets, Nir Yosef, Ellen A Robey

Institutions: University of California, Berkeley, Ragon Institute of MGH, MIT and Harvard

Language: English

Topic: T-cell and B-cell Immunology

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

Open Access status: gold

OpenAlex ID: W3162856777

Cites:

Cited by: 1

Related to: 10